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10.1210/en.2011-1170 [DOI] [PMC free article] [PubMed] [Google Scholar] 82.Yang L, Di G, Qi X, Qu M, Wang Y, Duan H, et al

patent issued, the USPTO held that the entire period from the RCE filing to the NO IDS filing (646 days) constituted applicant delay, which it deducted from over 2,000 days of USPTO delay that occurred during prosecution

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This is why the four-week minimum at each escalation tier is not arbitrary

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